Glutamate Transporter GLT1 Expression in Alzheimer Disease and Dementia With Lewy Bodies
نویسندگان
چکیده
منابع مشابه
Personality traits distinguishing dementia with Lewy bodies from Alzheimer disease.
OBJECTIVE To identify personality traits that distinguish dementia with Lewy bodies (DLB) from Alzheimer disease (AD). METHODS We examined 290 participants enrolled in a longitudinal study (nondemented control = 34, DLB = 128, AD = 128) followed to autopsy. As part of the annual interview with the collateral source, the clinician asked about specific changes in personality, interests, and dri...
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Dementia with Lewy (DLB) bodies is the most common type of degenerative dementia after Alzheimer Disease (AD). Although an accurate diagnosis of DLB is important for adequate prognosis and therapy, its differentiation from other dementias and, especially, from AD may be extremely challenging for clinicians, as highlighted by the high variability in reported sensitivity (0.22 – 0.83) and specifi...
متن کاملDementia with Lewy bodies and Parkinson's disease.
Lewy bodies (LB) in the central nervous system are associated with several different clinical syndromes including Parkinson's disease (PD) and dementia with Lewy bodies (DLB). Long term follow up of PD patients finds up to 78% eventually develop dementia, most of these patients exhibiting fluctuating cognition and visual hallucinations similar to DLB and with extensive cortical LB at autopsy. a...
متن کاملIn vivo assessment of vesicular monoamine transporter type 2 in dementia with lewy bodies and Alzheimer disease.
OBJECTIVE To assess the diagnostic potential of imaging striatal monoaminergic terminal integrity with the vesicular monoamine transporter type 2 (VMAT2) radioligand (18)F 9-fluropropyl-(+)-dihydrotetrabenazine ([(18)F]AV-133) and positron emission tomography to distinguish dementia with Lewy bodies (DLB) from Alzheimer disease (AD). DESIGN, SETTING, AND PARTICIPANTS Nine patients with DLB, 1...
متن کاملLewy body disease and dementia with Lewy bodies
In 1976 we reported our first autopsied case with diffuse Lewy body disease (DLBD), the term of which we proposed in 1984. We also proposed the term "Lewy body disease" (LBD) in 1980. Subsequently, we classified LBD into three types according to the distribution pattern of Lewy bodies: a brain stem type, a transitional type and a diffuse type. Later, we added the cerebral type. As we have propo...
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ژورنال
عنوان ژورنال: Frontiers in Aging Neuroscience
سال: 2018
ISSN: 1663-4365
DOI: 10.3389/fnagi.2018.00122